Background The field of personal health monitoring (PHM) develops rapidly in different contexts, including the armed forces. Understanding the ethical dimension of this type of monitoring is key to a morally responsible development, implementation and usage of PHM within the armed forces. Research on the ethics of PHM has primarily been carried out in civilian settings, while the ethical dimension of PHM in the armed forces remains understudied. Yet, PHM of military personnel by design takes place in a different setting (...) than PHM of civilians, because of their tasks and the context in which they operate. This case study therefore focusses on obtaining insights into the experiences and related values of different stakeholders regarding an existing form of PHM, the Covid-19 Radar app, in the Netherlands Armed Forces. Methods We carried out an exploratory qualitative study, using semi-structured interviews with twelve stakeholders in the Netherlands Armed Forces. We focussed on participation in the use of PHM, reflections on the practical use and use of data, moral dilemmas and the need for ethics support, all in regard to PHM. The data was analysed using an inductive thematic approach. Results Three interlinking categories reflecting ethical dimensions of PHM emerged: (1) values, (2) moral dilemmas, and (3) external norms. The main values identified were: security (in relation to data), trust and hierarchy. Multiple related values were found. Some, but no broadly shared, moral dilemmas were identified and no strong need for ethics support was expressed. Conclusion This study shed light on key values, provide insights in the experienced and presumed moral dilemmas and bring to mind ethics support considerations when looking at PHM in the armed forces. Some values bring a certain vulnerability to military users when personal and organisational interests are not aligned. Furthermore, some identified values may hinder a careful consideration of PHM because they potentially conceal parts of ethical dimensions of PHM. Ethics support can assist in uncovering and addressing these concealed parts. The findings highlight a moral responsibility for the armed forces to devote attention to the ethical dimensions of PHM. (shrink)

Recent experiments have shown that naive speakers find borderline contradictions involving vague predicates acceptable. In Cobreros et al. we proposed a pragmatic explanation of the acceptability of borderline contradictions, building on a three-valued semantics. In a reply, Alxatib et al. show, however, that the pragmatic account predicts the wrong interpretations for some examples involving disjunction, and propose as a remedy a semantic analysis instead, based on fuzzy logic. In this paper we provide an explicit global pragmatic interpretation rule, based on (...) a somewhat richer semantics, and show that with its help the problem can be overcome in pragmatics after all. Furthermore, we use this pragmatic interpretation rule to define a new consequence-relation and discuss some of its properties. (shrink)

The principle of tolerance characteristic of vague predicates is sometimes presented as a soft rule, namely as a default which we can use in ordinary reasoning, but which requires care in order to avoid paradoxes. We focus on two ways in which the tolerance principle can be modeled in that spirit, using special consequence relations. The first approach relates tolerant reasoning to nontransitive reasoning; the second relates tolerant reasoning to nonmonotonic reasoning. We compare the two approaches and examine three specific (...) consequence relations in relation to those, which we call: strict-to-tolerant entailment, pragmatic-to-tolerant entailment, and pragmatic-to-pragmatic entailment. The first two are nontransitive, whereas the latter two are nonmonotonic. (shrink)

Both the concept of a Darwinian tree of life (TOL) and the possibility of its accurate reconstruction have been much criticized. Criticisms mostly revolve around the extensive occurrence of lateral gene transfer (LGT), instances of uptake of complete organisms to become organelles (with the associated subsequent gene transfer to the nucleus), as well as the implications of more subtle aspects of the biological species concept. Here we argue that none of these criticisms are sufficient to abandon the valuable TOL concept (...) and the biological realities it captures. Especially important is the need to conceptually distinguish between organismal trees and gene trees, which necessitates incorporating insights of widely occurring LGT into modern evolutionary theory. We demonstrate that all criticisms, while based on important new findings, do not invalidate the TOL. After considering the implications of these new insights, we find that the contours of evolution are best represented by a TOL. (shrink)

Artificial intelligence (AI) and machine learning (ML) are increasingly integrated into the functioning of physical and digital products, creating unprecedented opportunities for interaction and functionality. However, there is a challenge for designers to ideate within this creative landscape, balancing the possibilities of technology with human interactional concerns. We investigate techniques for exploring and reflecting on the interactional affordances, the unique relational possibilities, and the wider social implications of AI systems. We introduced into an interaction design course (_n_ = 100) nine (...) ‘AI exercises’ that draw on more than human design, responsible AI, and speculative enactment to create experiential engagements around AI interaction design. We find that exercises around metaphors and enactments make questions of training and learning, privacy and consent, autonomy and agency more tangible, and thereby help students be more reflective and responsible on how to design with AI and its complex properties in both their design process and outcomes. (shrink)

Background The COVID-19 pandemic causes moral challenges and moral distress for healthcare professionals and, due to an increased work load, reduces time and opportunities for clinical ethics support services. Nevertheless, healthcare professionals could also identify essential elements to maintain or change in the future, as moral distress and moral challenges can indicate opportunities to strengthen moral resilience of healthcare professionals and organisations. This study describes 1) the experienced moral distress, challenges and ethical climate concerning end-of-life care of Intensive Care Unit (...) staff during the first wave of the COVID-19 pandemic and 2) their positive experiences and lessons learned, which function as directions for future forms of ethics support. Methods A cross-sectional survey combining quantitative and qualitative elements was sent to all healthcare professionals who worked at the Intensive Care Unit of the Amsterdam UMC - Location AMC during the first wave of the COVID-19 pandemic. The survey consisted of 36 items about moral distress (concerning quality of care and emotional stress), team cooperation, ethical climate and (ways of dealing with) end-of-life decisions, and two open questions about positive experiences and suggestions for work improvement. Results All 178 respondents (response rate: 25–32%) showed signs of moral distress, and experienced moral dilemmas in end-of-life decisions, whereas they experienced a relatively positive ethical climate. Nurses scored significantly higher than physicians on most items. Positive experiences were mostly related to ‘team cooperation’, ‘team solidarity’ and ‘work ethic’. Lessons learned were mostly related to ‘quality of care’ and ‘professional qualities’. Conclusions Despite the crisis, positive experiences related to ethical climate, team members and overall work ethic were reported by Intensive Care Unit staff and quality and organisation of care lessons were learned. Ethics support services can be tailored to reflect on morally challenging situations, restore moral resilience, create space for self-care and strengthen team spirit. This can improve healthcare professionals’ dealing of inherent moral challenges and moral distress in order to strengthen both individual and organisational moral resilience. Trial registration The trial was registered on The Netherlands Trial Register, number NL9177. (shrink)

This paper concludes a special feature of Sustainability Science that explores a broad range of social value theoretical traditions, such as religious studies, social psychology, indigenous knowledge, economics, sociology, and philosophy. We introduce a novel transdisciplinary conceptual framework that revolves around concepts of 'lenses' and 'tensions' to help navigate value diversity. First, we consider the notion of lenses: perspectives on value and valuation along diverse dimensions that describe what values focus on, how their sociality is envisioned, and what epistemic and (...) procedural assumptions are made. We characterise fourteen of such dimensions. This provides a foundation for exploration of seven areas of tension, between: (1) the values of individuals vs collectives; (2) values as discrete and held vs embedded and constructed; (3) value as static or changeable; (4) valuation as descriptive vs normative and transformative; (5) social vs relational values; (6) different rationalities and their relation to value integration; (7) degrees of acknowledgment of the role of power in navigating value conflicts. In doing so, we embrace the 'mess' of diversity, yet also provide a framework to organise this mess and support and encourage active transdisciplinary collaboration. We identify key research areas where such collaborations can be harnessed for sustainability transformation. Here it is crucial to understand how certain social value lenses are privileged over others and build capacity in decision-making for understanding and drawing on multiple value, epistemic and procedural lenses. (shrink)

This paper concludes a special feature of Sustainability Science that explores a broad range of social value theoretical traditions, such as religious studies, social psychology, indigenous knowledge, economics, sociology, and philosophy. We introduce a novel transdisciplinary conceptual framework that revolves around concepts of ‘lenses’ and ‘tensions’ to help navigate value diversity. First, we consider the notion of lenses: perspectives on value and valuation along diverse dimensions that describe what values focus on, how their sociality is envisioned, and what epistemic and (...) procedural assumptions are made. We characterise fourteen of such dimensions. This provides a foundation for exploration of seven areas of tension, between: (1) the values of individuals vs collectives; (2) values as discrete and held vs embedded and constructed; (3) value as static or changeable; (4) valuation as descriptive vs normative and transformative; (5) social vs relational values; (6) different rationalities and their relation to value integration; (7) degrees of acknowledgment of the role of power in navigating value conflicts. In doing so, we embrace the ‘mess’ of diversity, yet also provide a framework to organise this mess and support and encourage active transdisciplinary collaboration. We identify key research areas where such collaborations can be harnessed for sustainability transformation. Here it is crucial to understand how certain social value lenses are privileged over others and build capacity in decision-making for understanding and drawing on multiple value, epistemic and procedural lenses. (shrink)

Cancers often express hundreds of genes otherwise specific to germ cells, the germline/cancer (GC) genes. Here, we present and discuss the hypothesis that activation of a “germline program” promotes cancer cell malignancy. We do so by proposing four hallmark processes of the germline: meiosis, epigenetic plasticity, migration, and metabolic plasticity. Together, these hallmarks enable replicative immortality of germ cells as well as cancer cells. Especially meiotic genes are frequently expressed in cancer, implying that genes unique to meiosis may play a (...) role in oncogenesis. Because GC genes are not expressed in healthy somatic tissues, they form an appealing source of specific treatment targets with limited side effects besides infertility. Although it is still unclear why germ cell specific genes are so abundantly expressed in cancer, from our hypothesis it follows that the germline's reproductive program is intrinsic to cancer development. (shrink)

ABSTRACTThis is a lightly edited transcript of a plenary talk given at the Beyond Positivism conference, Montreal, August 8–10 2017. The talk followed others by Christopher Winship and Frédéric Van...

Several gaze contingent studies that used a fixed delay between physical eye movements and a display change documented a dip in the fixation duration distributions (e.g., Blanchard et al. 1984; McConkie et al. 1985; van Diepen et al. 1995). In a study by van Diepen et al. (1995), a moving mask paradigm was employed in which subjects searched line drawings of everyday scenes for non-objects. The appearance of the mask was delayed relative to the end of a saccade (beginning of (...) fixation) by 17, 46, 76 or 121 msec. All fixation duration distributions in the masking conditions exhibited a dip with longer masking delays resulting in the dip occurring at longer fixation durations. In contrast, a no-mask condition did not produce a dip. Similar effects in reading were reported by Blanchard et al. (1984), and McConkie et al. (1985). In both these studies the text was.. (shrink)

Obwohl sie durch das Werk von MoNTESQUIEU erst auf die praktische Staatskunst von Einfluss geworden ist, so ist doch die Lehre der drei Staatsfunktionen schon von sehr altem Datum. Die Spuren einer Einteilung der Staatsaufgabe kann man bereits 1 bei ARISTOTELES finden. Er unterscheidet in der Politica ) drei Elemente. Das Verhältnis dieser die Staatsaufgabe konstituierenden Elemente ist verschieden und charakteristisch für den Regierungs typus, und ARISTOTELES hält es für die Pflicht des Gesetzgebers, eines und das andre so anzuordnen, (...) wie es sich für jede Gemein schaft passt. Man kann dann nach ARISTOTELES unterscheiden, erstens die beratende Funktion, welche die autoritative Beschluss fassung über Krieg und Frieden, das Schliessen oder Brechen von Bündnissen, die Verfassung von Gesetzen, das Treffen von Ent scheidungen über 'Todesstrafe, Verbannung und Konfiskation, sowie die Anstellung von Magistraten umfasst. Daneben nennt ARISTOTELES die vollziehende Funktion der Obrigkeit und die richterliche Funktion. 2 JEAN BoDIN ) kommt bei der Analysierung der Souveränität zu fünf Elementen, nämlich Gesetzgebung, Entscheidung über Krieg und Frieden, Ernennung von Beamten, Rechtsprechung und Begnadigung. (shrink)

Der Streit darüber, ob es objektive Wahrheitskriterien gibt, wird oft mit der Frage vermengt, ob Wissenschaft immer fortschreite. Vor allem Popper in "Objective Knowledge" unterstellt in starkem Maße einen allgemeinen Trend der Wissenschaft zum Fortschritt. In diesem Beitrag wird gezeigt, daß Wissen verloren gehen kann: 1. Weil es nicht aufgezeichnet wird; 2. weil die Dokumente, in denen es niedergelegt wurde, verloren gehen; 3. weil das Wissen um die Sprache der Dokumente, in denen es niedergelegt wurde, verloren gegangen ist, 4. (...) weil die spätere Wissenschaftlergemeinschaft die Dokumente nicht genügend beachtet, in denen es niedergelegt wurde. Der Verlust nichtaufgezeichneten Wissens ist äußerst üblich. Der Verlust veröffentlichter Dokumente war besonders vor der Erfindung der Drucktechnik häufig und hat besonders in manchen Zweigen der Geisteswissenschaften einen Rückschritt bedeutet, weil entweder Dokumente, die das Objekt dieser Wissenschaften ausmachen , oder Aufzeichnungen historischer Ereignisse verloren gingen. Der Verlust veröffentlichter Dokumente nach der Erfindung der Drucktechnik war etwas weniger bedeutend, aber er kam dennoch vor. Der Verlust unveröffentlichter Dokumente geschah häufig, und zwar sowohl vor wie nach der Erfindung der Drucktechnik. Ob in unentzifferten Dokumenten definitiv Wissensverlust vorliegt, ist einigermaßen zweifelhaft. Einige unentzifferte Sprachen mögen eines Tages entziffert werden, aber einige unentzifferte Sprachen mögen auch für immer unentziffert bleiben. Der Verlust von Wissen wegen unzureichender Aufmerksamkeit gegenüber dem Werk eines früheren Wissenschaftlers kann behoben werden, wenn man seine Behauptungen nochmals untersucht. Wissensverlust kommt hauptsächlich in den Geisteswissenschaften vor. In der Mathematik und einigen Naturwissenschaften gibt es fast nur Zunahme an Wissen wegen der Wiederholbarkeit der Experimente. (shrink)

Der Beweis des Vierfarbensatzes mit Hilfe eines Computers, der so viel Zeit erforderte, daß ein Mensch die Berechnungen niemals überprüfen könnte, hat Zweifel erregt an vier philosophischen Annahmen über Mathematik. Die Mathematik ist die Lehre der Klassifikation, insoweit als sie vollständig abstrahiert von der Art der zu klassifizierenden Dinge. Diese Auffassung wird vom Beweis des Vierfarbensatzes nicht erschüttert. Wahrscheinlich kann mathematisches Denken nicht vor sich gehen ohne sinnliche Vorstellungen, aber die Eigenschaften mathematischer Gegenstände sind unabhängig von ihrer Weise sinnlicher (...) Vorstellung. (shrink)

Die Synagoge ist das dritte der fünf großen byzantinischen Lexika: Kyrill, Hesych, Synagoge, Photios, Suda. Im Kyrill-Lexikon war erstmals der Wortschatz der heidnischen, hellenistischjüdischen und frühen christlichen griechischen Literatur gesammelt. Es ist in Hesych nachträglich eingearbeitet; etwa ein Drittel des „Hesych“ stammt aus „Kyrill“. Kyrill ist in der Synagoge exzerpiert; etwa 80 Prozent ihrer Glossen lassen sich auf ihn zurückführen, und sie kann durchaus als Kyrill-Rezension angesehen werden, wie es in einer ihrer Handschriften geschieht (vgl. p. 19, 49). Die (...) Synagoge ist nahezu vollständig in Photios und Suda eingearbeitet, und zwar nach der zweiten ihrer beiden überlieferten Rezensionen. (shrink)

This analysis of the relation between virtue and knowledge focuses on the following aspects: i) Virtue and Happiness can be objects of knowledge; ii) Virtue is knowledge; iii) The search for knowledge is aiming at – and justified by – the human to be happy. Plato therefore defines philosophy not as theory but as the search for wisdom in order to live well. Accordingly Plato does not distinguish different or independent branches of philosophy. These conclusions are reached by an investigation, (...) which traces the continuity and the development of the relation between virtue and knowledge throughout the different phases in Plato's philosophy. The leading thesis of this book is unitarian, but in order to corroborate it the methodology is used of those scholars who think that Plato's philosophy has changed significantly through the dialogic phase. This way, it can be shown that Plato kept developing new justifications for the same relation between virtue and knowledge.Diese Untersuchung der Beziehung von Tugend und Wissen konzentriert sich auf folgende Aspekte: i) Sowohl Tugend als auch Wissen können erkannt werden; ii) Tugend ist Wissen; iii) Die Wissenssuche wird durch das Glücksstreben finalisiert. Daher bestimmt Platon Philosophie nicht als Theorie, sondern als Suche nach der Weisheit, um glücklich zu leben. Entsprechend unterscheidet Platon keine Teilbereiche der Philosophie, die unabhängige Ziele verfolgen. Diese Schlussfolgerungen werden erreicht durch eine Untersuchung, die die Kontinuität und Entwicklung der Beziehung von Tugend und Wissen durch die verschiedenen Phasen in der Platonischen Philosophie verfolgt. Die leitende These ist unitarisch, aber um sie zu bestätigen wird die Methode derjenigen verwandt, die annehmen, die Platonische Philosophie hätte sich in durch die Dialogphasen wesentlich entwickelt. So kann gezeigt werden, dass Platon immer neue Begründungen für dieselbe Beziehung von Tugend und Wissen entwickelt hat. (shrink)

In den Jahren, aud denen WL stammt , legt Nietzsche ein beachtenswertes Interesse für Aristoteles' politische Philosophie an den Tag, und WL kann aus der Perspektive einer Passage der aristotelischen Politik gelesen werden. In beiden Texten geht es um Wahrheit, Moral und Gemeinschaft. Während Aristoteles zufolge der Mensch als Logos-Wesen wesentlich in einer politischen Gesellschaft lebt und somit sich vom Tier und vom Gott unterscheidet, such Nietzsche nach einer Figue, die beide - gegensätzlichen - Positionen in sich vereint. Der (...) Philosoph, den Nietzsche sucht und der er sein will, muss sich einerseits außerhalb Gemeinschaft stellen, von welcher er andererseits Teil sein muss, um sein Aufgabe erfüllen zu können. Er muss sowohl Gott als auch Tier sein. Dass Nietzsche diese Figur jetzt noch nicht findet, macht seinen Text 'unfertig' und erklärt vielleicht, dass er 'geheimgehalten' werden musste.During the years in which Nietzsche write his essay On Truth and Lies in a Nonmoral Sense , he seems to have paid a remarkable interest to Aristotle's political philosophy, and TL can be read against the background of a passage from Aristotle's Politics . Both texts concern the relationship between truth, morality, and society. While, according to Aristotle, the human being is, as a logos-being, essentially a political being and therefore to be distinguished from animals as well as from god, Nietzsche seems to be searching for a being which brings both - contradictory - positions together. The philosopher whom he searches for and tries to be, should on the one hand distance himself from society in which he, on the other hand, should participate in order to be able to fulfill his task. He should be god and animal at the same time. Nietzsche does not find this figure yet, which makes his text unfinished and perhaps explains why he had to keep it secret. (shrink)

Der Streit darüber, ob es objektive Wahrheitskriterien gibt, wird oft mit der Frage vermengt, ob Wissenschaft immer fortschreite. Vor allem Popper in "Objective Knowledge" unterstellt in starkem Maße einen allgemeinen Trend der Wissenschaft zum Fortschritt. In diesem Beitrag wird gezeigt, daß Wissen verloren gehen kann: 1. Weil es nicht aufgezeichnet wird; 2. weil die Dokumente, in denen es niedergelegt wurde, verloren gehen; 3. weil das Wissen um die Sprache der Dokumente, in denen es niedergelegt wurde, verloren gegangen ist, 4. (...) weil die spätere Wissenschaftlergemeinschaft die Dokumente nicht genügend beachtet, in denen es niedergelegt wurde. Der Verlust nichtaufgezeichneten Wissens ist äußerst üblich. Der Verlust veröffentlichter Dokumente war besonders vor der Erfindung der Drucktechnik häufig und hat besonders in manchen Zweigen der Geisteswissenschaften einen Rückschritt bedeutet, weil entweder Dokumente, die das Objekt dieser Wissenschaften ausmachen, oder Aufzeichnungen historischer Ereignisse verloren gingen. Der Verlust veröffentlichter Dokumente nach der Erfindung der Drucktechnik war etwas weniger bedeutend, aber er kam dennoch vor. Der Verlust unveröffentlichter Dokumente geschah häufig, und zwar sowohl vor wie nach der Erfindung der Drucktechnik. Ob in unentzifferten Dokumenten definitiv Wissensverlust vorliegt, ist einigermaßen zweifelhaft. Einige unentzifferte Sprachen mögen eines Tages entziffert werden, aber einige unentzifferte Sprachen mögen auch für immer unentziffert bleiben. Der Verlust von Wissen wegen unzureichender Aufmerksamkeit gegenüber dem Werk eines früheren Wissenschaftlers kann behoben werden, wenn man seine Behauptungen nochmals untersucht. Wissensverlust kommt hauptsächlich in den Geisteswissenschaften vor. In der Mathematik und einigen Naturwissenschaften gibt es fast nur Zunahme an Wissen wegen der Wiederholbarkeit der Experimente. (shrink)

I agree with Van Parijs that a theory of justice must meet the condition of indicating institutions that eliminate compulsory unemployment, but argue that his basic income is another form of unemployment compensation with all the disadvantages such compensations suffer from. In particular, it does not advance real freedom, but is liable to contribute to narrow political ends. I indicate an alternative and explicate, since Van Parijs disregards it, the right to work and its basis in the common property of (...) natural resources. Finally, I compare the two competing conceptions of a good life that underlie his recommendation of a basic income and my rejection of it. (shrink)

In his recent book Willensfreiheit Geert Keil defends a version of libertarianism. Yet he criticizes a flagship argument for incompatibilism. Van Inwagen's consequence argument, Keil thinks, relies on an irrelevant premise when it claims that agents have no choice about the remote past. I argue that Keil's charge rests on a misunderstanding. I then sketch why discussions of the consequence argument should focus on the question whether or not a certain version of rule Beta is valid.

I first met Hans Albert in 1974, when together with two friends, Rob de Vries and Berry van Berkel, I participated in the European Forum Alpbach for the first time. We attended the seminar that was led by John Watkins and Walter Kaufmann and, of course, went to as many of the plenary meetings as possible. At the time, the seminar week and the bulk of the plenary events were still organized during the same period and were included in the (...) fee, neither of which is unfortunately the case any longer. (shrink)

Neurotheology is a fast-growing field of research. Combining philosophy of mind, neuroscience, and religious studies, it takes a new approach to old questions on religion. What is religion and why do we have it? Neurotheologists focus on the search for the neural correlate of religious experiences. If we can trace religious experiences to specific parts of the brain, chances are we can reduce religion as such to that grey soggy matter as well. This article predicts neurotheology will not be able (...) to locate the neural correlate of religious experiences. As we cannot decide phenomenally what makes an experience religious, neurologically we cannot find its correlate either. That is, if there are fixed neural correlates to begin with, because their existence is still a matter of debate. In addition, religious experiences seem to be a kind of experience, like emotional or relational experiences, making them indistinguishable from similar nonreligious experiences. Even if one manages to trace the neural correlate of religious experiences, neurotheology will still not be able to account for the rise of religion without resorting to theories from other disciplines. In the end, we do not know enough about consciousness and the way it relates to the brain to make conclusive claims about the search for religious states of consciousness. It seems, however, that even though neurotheology could provide fascinating insights in the workings of the religious brain, on its own, it will prove unable to explain religion fully. (shrink)

Inner membranes of mitochondria are extensively folded, forming cristae. The observed overall correlation between efficient eukaryotic ATP generation and the area of internal mitochondrial inner membranes both in unicellular organisms and metazoan tissues seems to explain why they evolved. However, the crucial use of molecular oxygen (O2) as final acceptor of the electron transport chain is still not sufficiently appreciated. O2 was an essential prerequisite for cristae development during early eukaryogenesis and could be the factor allowing cristae retention upon loss (...) of mitochondrial ATP generation. Here I analyze illuminating bacterial and unicellular eukaryotic examples. I also discuss formative influences of intracellular O2 consumption on the evolution of the last eukaryotic common ancestor (LECA). These considerations bring about an explanation for the many genes coming from other organisms than the archaeon and bacterium merging at the start of eukaryogenesis. (shrink)

Blackshaw and Hendricks have recently developed and defended the impairment argument against abortion, arguing that the immorality of giving a child fetal alcohol syndrome (FAS) provides us with reason to believe that abortion is immoral. In this paper, we forward two criticisms of the impairment argument. First, we highlight that, as it currently stands, the argument is very weak and accomplishes very little. Second, we argue that Blackshaw and Hendricks are fundamentally mistaken about what makes giving a child FAS immoral. (...) Once we acknowledge this, it is clear that our intuitions about giving a child FAS provide no support for the supposed immorality of abortion. (shrink)

This introduction to a special issue of Topoi introduces and summarises the relationship between three main varieties of 'enactivist' theorising about the mind: 'autopoietic', 'sensorimotor', and 'radical' enactivism. It includes a brief discussion of the philosophical and cognitive scientific precursors to enactivist theories, and the relationship of enactivism to other trends in embodied cognitive science and philosophy of mind.

Ethical challenges in genomic epidemiology are the direct result of novel tools used to confront scientific challenges in the field. An orders-of-magnitude increase in scale of genetic data collection has created the need for establishing diffuse international partnerships, sometimes across developed- and developing-world countries, with ramifications for assigning research ownership, distributing intellectual property rights, and encouraging capacity-building. Meanwhile, the fact that genomic epidemiological research is so far upstream in the pipeline of therapy development has implications for the privacy rights of (...) research participants and for a rigorous definition of valid informed consent, particularly in resource-poor settings. From these scientific underpinnings, we distill out two main categories of ethical issues: (1) How should researchers ensure that the subjects of research are appropriately protected? and (2) What is the structure of an equitable and fair system for distributing the financial and scientific rewards of research? We attempt to delineate the contours of specific problems in each category and propose steps toward solutions with reference to a particular project, known as gMap.net, that focuses on genomic epidemiological studies of malaria. (shrink)

An eye-opening tour of the political tricks that subvert scientific progress. The Butter-Up and Undercut. The Certain Uncertainty. The Straight-Up Fabrication. Dave Levitan dismantles all of these deceptive arguments, and many more, in this probing and hilarious examination of the ways our elected officials attack scientific findings that conflict with their political agendas. The next time you hear a politician say, "Well, I’m not a scientist, but…," you’ll be ready.

This article aims to demonstrate how the formation of ethical subjectivity must be considered in conjunction with the techno-politics of secrecy and disclosure, and it proposes an account of the ways in which the technical transition and ‘democratization’ of archival upload/download capacity associated with digital communications fundamentally challenges the existing structure of control over such things as censorship and cultural memory understood in terms of power of recall. It argues that it is against this background and in view of the (...) mediality of communications that the question of responsibility with respect to secrets and their disclosure must ultimately be posed. It seeks to establish the difference between a purely political and an ethico-political understanding of the secrecy/disclosure dyad as this functions, on the one hand, in relation to philosophical inquiry itself and, on the other, in relation to normative representations of informational events, and it contextualizes its theoretical account of this difference in relation to the ‘Wikileaks phenomenon’ viewed as a disclosive event. It examines how ethical subjectivity is formed in relation to ‘information’ and in the wider context of a digital culture of archivization, characterized by the ubiquitous recording of communications of all kinds. Drawing centrally on the ethical philosophy of Emmanuel Levinas, for whom ‘infinite responsibility’ is ‘incarnated’ as the ‘ultimate secret of subjectivity’ in me, and Derrida’s account of both the necessary technicity of the human and the impossibility of ‘saying the event’, it proposes a way of thinking the ethico-techno-politics of secrecy and disclosure in terms of the singularity of the event and the unique responsibility of the ethical Subject in relation to that. (shrink)

What is it to be an agent? One influential line of thought, endorsed by G. E. M. Anscombe and David Velleman, among others, holds that agency depends on practical rationality—the ability to act for reasons, rather than being merely moved by causes. Over the past 25 years, Velleman has argued compellingly for a distinctive view of agency and the practical rationality with which he associates it. On Velleman’s conception, being an agent consists in having the capacity to be motivated by (...) a drive to act for reasons. Your bodily movements qualify as genuine actions insofar as they are motivated in part by your desire to behave in a way that makes sense to yourself. However, there are at least two distinct ways of spelling out what this drive towards self-intelligibility consists in, both present in Velleman’s work. It might consist in a drive towards intelligibility in causal-psychological terms: roughly, a drive to maximize the rational coherence of your psychological states. Alternatively, it might consist in a drive towards narrative intelligibility: a drive to make your ongoing activity conform to a recognizable narrative structure, where that structure is understood emotionally. Velleman originally saw these options as basically equivalent, but later came to prioritize the drive towards causal-psychological intelligibility over that towards narrative intelligibility. I argue that this gets things the wrong way round—we should instead understand our capacities to render ourselves intelligible in causal-psychological terms as built upon a bedrock of emotionally suffused narrative understanding. In doing so, we resolve several problems for Velleman’s view, and pave the way for an embodied, embedded and affective account of practical rationality and agency. According to the picture that emerges, practical rationality is essential to agency, narrative understanding is essential to practical rationality, and the rhythms and structures patterning the ebb and flow of our emotional lives are essential to narrative understanding. (shrink)

Many teacher candidates get their first taste of life as a full-time teacher in their practicums, during which they confront a host of challenges, pedagogical and ethical. Because ethics is fundamental to the connection between teachers and students, teacher candidates are often required to negotiate dilemmas in ways that keep with the ethical ideals espoused both by the professional body and the community at large. Presenting the case of a teacher candidate who finds herself emotionally depleted in her devotion to (...) students, we look to the ethics of care and virtue for clarifying insights. Care ethics extols intersubjectivity and reciprocity, while virtue ethics enjoins commitment to a noble ideal for its own sake; both perspectives offer useful insights for our case. We argue that the perspectives and practices of contemplative traditions can facilitate the integration of care and virtue ethics, mitigating the risk of disruption in caring relations while minimizing the possibility of a personal p... (shrink)

Metaphysicians speak of laws of nature in terms of necessity and universality; scientists, in terms of symmetry and invariance. In this book van Fraassen argues that no metaphysical account of laws can succeed. He analyzes and rejects the arguments that there are laws of nature, or that we must believe there are, and argues that we should disregard the idea of law as an adequate clue to science. After exploring what this means for general epistemology, the author develops the empiricist (...) view of science as a construction of models to represent the phenomena. (shrink)

Heidegger ist durch seinen eigenwilligen Sprachgebrauch einer der dunkelsten Denker unserer Zeit. Dies ist jedoch kein Zeichen von Willkür oder unbegründeter Sucht nach Ürsprünglichkeit, für ihn hängt die Sprache wesentlich mit seinem Philosophieren zusammen (1). Vor allem ist von Seiten der angloamerikanischen Sprachanalytiker an diesem Sprachgebrauch viel Kritik geübt, u.a. durch Carnap. Ausdrücke wie „das Nichtige nichtet” finden in den empirischen Situationen kein Echo, entziehen sich der Methode der Verifikation, erfüllen keine einzige Wahrheitsvoraussetzung und können keine Protokollsätze sein (2). Dennoch, (...) Heideggers Methode kann, vermöge der Art seiner Untersuchung, der Frage nach dem Sinn des Seins, nicht die der logischen Analyse sein ; sie ist die phänomenologische Methode, die für die Ontologie in ihren Fragen nach dem Sinn des Seins die angemessenste Methode ist (3). Heidegger meint, daß die Vorsokratiker in ihrer dichterischen Formgebung dem ursprünglichen Sinn des Seins äußerst nahegekommen sind. Seine Intention beschränkt sich nicht allein auf eine etymologische Analyse von Begriffen wie „physis”, „logos”, „aletheia” usw., wodurch er das Sein zu entbergen sucht, er will mit dieser Analyse auch und vor allem ein neues Fundament legen für unser heutiges Denken und unsere Einstellung dem Sein gegenüber (4). Um dies deutlich zu machen, wählen wir Heideggers Auseinandersetzung mit dem Logosbegriff bei Heraklit im Fragment 50 (Diels), den er in Vorträge und Aufsätze III (Pfüfflingen 1967, S. 3-25) einer minuziösen Untersuchung unterzieht. Heidegger fragt sich, was die ursprüngliche Bedeutung von Logos ist, und er sucht zu beweisen, daß „legein” nicht ursprünglich „sprechen” bedeutet, sondern in dem deutschen „legen” (vorlegen, darlegen, überlegen) wiedergefunden wird, „legein” konnte sprechen bedeuten, weil sprechen besagt : „Beisammen-vor-uns-liegen-lassen”. Deshalb kann nach Heidegger die Sprache nicht als „Verlautbarung” oder „Bedeuten” gedeutet werden. Ausdruck und Bedeutung sind beide Phänomene der Sprache als das „Beisammen-voruns-liegen-lassen” des Unverborgenen in seiner Unverborgenheit. Das Sprechen muß nach Heidegger den Spielraum der Unverborgenheit, mit dem das Hören korrespondieren muß, offenlassen. Das Hören nach dem Logos ist ein „homologein”, dem Logos zugehörig. Ist man dem Logos zugehörig, so ist man in dem Sinne weise, daß man sich in das schickt (geschicklich), was dem Menschen zugewiesen ist : Heidegger widersetzt sich der herrschenden Interpretation von Fr. 50. Das „Eins-Alles” zielt nicht auf den Inhalt der Verkündigung des Logos, sondern vielmehr auf die Weise, in der der Logos anwesend ist, die Weise, in der er wirkt und wohl als das Eine, das alles ausschließt, das lichtende Sammeln, Zusammentragen, das Bergen aller Gegebenheiten in die Offenheit der Welt. Er birgt und entbirgt. Unverborgenheit und Verborgenheit sind Pole dieses einen Seinsereignisses. So bleiben die Gegensätze innerhalb des Lichtkreises der Unverborgenheit bestehen und aufeinander angewiesen. Heidegger identifiziert den Logos mit dem „Hen-Panta”, weil „ Hen-Panta” sagt, was der Logos ist, und der Logos sagt, wie „Hen-Panta” anwesend ist. Wenn der Mensch die Sprache des Logos spricht, sammelt er auch die Dinge, läßt er sie vor-sichliegen, bringt er die Anwesenheit der Dinge in ihrem Anwesen zur Sprache, läßt sie zu ihrem Recht kommen, dabei durch das ursprüngliche „Einen” des Logos geleitet, das „Hen-Panta” ist. Heidegger weist darauf hin, daß dies kein pantheistischer Gedankengang ist. Heraklit will, so meint er, vor dem Geheimnis dieser Worte stehenbleiben, um so das Geheimnis als Geheimnis zu erkennen. Er meint, daß der durch die Vorsokratiker geöffnete Weg durch die Denkentwicklung seit Plato verschleiert geblieben ist. Heidegger sieht in Fr. 50 von Heraklit den stammelnden Ausdruck des noch nicht in Subjekt und Objekt aufgeteilten Seins. In dem Wort Logos dachte Heraklit das Sein des Seienden. Dieses Licht verblaßte schnell. Für Heidegger liegt die große Bedeutung Heraklits in dessen Anregung, in Übereinstimmung mit der Logossprache zu sprechen und den Weg einzuschlagen, den er uns gezeigt hat durch ein uns Offenhalten für das entbergendverbergende Sein (5). Auf wirklich geniale Weise hat Heidegger der Logosphilosophie die Gewalt seines eigenen Denkens verliehen. Diese Auslegung lehrt uns mehr über seine eigene Philosophie, als über die Heraklits. Heidegger ist gefesselt durch das mystisch-prophetische Element in Heraklits Philosophieren. So wie Heraklit der Dolmetscher der Masse sein will, die dem Logos widerspricht, obwohl sie fortwährend darüber spricht, so fühlte Heidegger sich berufen ein Hermeneut zu sein, auf dem durch die Seinsvergessenheit verdunkelten Weg des denkens nach einem neuen (An) denken des Seins. Betroffen ist Heidegger durch die Idee der Einheit, die sich in dem Logos erschließt. Der Logos offenbart sich in der Welt durch Gegensätze, in denen die Einheit sich fortwährend erneuert. Das Denken Heideggers ist von Anfang an auf das Ans-Licht-bringen des (oft) vergessenen, verborgenen Zusammenhängens gerichtet, in dem alles was ist erscheint. Aus dieser Interpretation wird deutlich, wie wertvoll eine Konfrontation der eigenen Zeit mit der Vergangenheit sein kann, angesichts der Gratie, durch die die Geschichte der Philosophie aktuell bleibt (6). Unser großes Bedenken gegen diese Interpretation ist, daß Heidegger sich keine Rechenschaft über die textkritischen Schwierigkeiten dieses Textes gegeben hat. Es ist die Frage, ob wohl Logos im ursprünglichen Text gestanden hat. Wir haben versucht, dies aufzuzeigen. Gleichfalls ist es sehr bedenklich, daß Heidegger „legein” und „legen” etymologisch im Zusammenhang sieht, was deshalb nicht möglich ist, weil beide Wörter auf im Wesen verschiedene indoeuropäische Wurzeln zurückgehen. Unsere Schlußfolgerung ist, daß Heideggers Auslegung von Fr. 50 uns mehr über die Philosophie von Heidegger selbst, als über die Logosphilosophie von Heraklit lehrt. Es ist besonders zu bedauern, daß Heidegger, der sich gerne rühmt die Belange der Wissenschaftlichkeit zu vertreten, die für die Interpretation griechischer Texte unentbehrliche philologische Vorarbeit vernachlässigt hat. (shrink)

Key texts on beauty and its revival in contemporary art.

Dragon days: introduction to the new edition -- Enter the dragon: on the vernacular of beauty 1 -- Nothing like the son: on Robert Mapplethorpe's X portfolio -- Prom night in flatland: on the gender of works of art -- After the great tsunami: on beauty and the therapeutic institution -- American beauty.

Social and linguistic perceptions are linked. On one hand, talker identity affects speech perception. On the other hand, speech itself provides information about a talker's identity. Here, we propose that the same probabilistic knowledge might underlie both socially conditioned linguistic inferences and linguistically conditioned social inferences. Our computational–level approach—the ideal adapter—starts from the idea that listeners use probabilistic knowledge of covariation between social, linguistic, and acoustic cues in order to infer the most likely explanation of the speech signals they hear. (...) As a first step toward understanding social inferences in this framework, we use a simple ideal observer model to show that it would be possible to infer aspects of a talker's identity using cue distributions based on actual speech production data. This suggests the possibility of a single formal framework for social and linguistic inferences and the interactions between them. (shrink)

The development of immersive media-communication environments, and their theorization in terms of the `haptic', calls for a reconsideration of the relationship between sensuality and the ethics of contact. For the most part, the cultural theorization of the virtual which remains preoccupied with the visual has tended to limit its scope to the paradoxes, politics and ethics of representation. Much of media and cultural studies work, for instance, has adopted, directly or indirectly, the traditional visual and ocularcentric paradigm in its analyses (...) of cultural forms and technologies as these have become integrated into contemporary life. Whilst it has been argued, for instance by Mark Hansen in his recent books, that this paradigm is inadequate to digital media and the developments of human-machine interactions the digital introduces, few comentators have addressed how new developments in immersive sensory media environments bear on the ethics of communication. By way of a reflection on the themes of the tactility of contact and the ethics of touch in the work of Emmanuel Levinas, this article critically evaluates the ethical significance of the `sensory extension' haptic media represent. It identifies and argues against the neo-positivist tendency of Hansen's reliance on the empiricism of the neurosciences whilst locating the resources for an ethics of touch in Levinas' concept of time as `diachrony'. (shrink)